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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76780 | Onartuzumab | RG-3638,PRO-14396,MetMAb | c-Met/HGFR |
Onartuzumab (MetMAb) is a humanized anti-tyrosine kinase c-MET monovalent monoclonal antibody.Onartuzumab has antitumor activity with inhibitory effects on HGF binding, receptor phosphorylation, and signal transduction. | |||
T37596 | Terevalefim | c-Met/HGFR | |
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. | |||
TP1990 | Norleual | ||
Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic. | |||
T76745 | Ficlatuzumab | ||
Ficlatuzumab, a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF), impedes the HGF/c-Met signaling pathway. By blocking this pathway, it prevents c-Met receptor-mediated cancer cell proliferation,... | |||
T71187 | Foretinib phosphate | ||
Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vas... | |||
T28240 | Ono 1301 | Ono-1301,Ono1301 | |
Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only wit... | |||
T75940 | Norleual TFA | ||
Norleual TFA, an analog of angiotensin (Ang) IV, functions as a hepatocyte growth factor (HGF)/c-Met inhibitor, displaying a potent inhibition capability with an IC50 of 3 pM. Additionally, it acts as an AT4 receptor ant... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01896 | HGFR/c-Met Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
HGFR/c-Met Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 102 kDa and the accession number is EDL13881.1. | |||
TMPK-00457 | HGFR/c-Met Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ... | |||
TMPJ-00415 | HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated | Human | HEK293 Cells |
Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un... | |||
TMPK-00499 | HGFR/c-Met Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ... | |||
TMPY-01895 | HGFR/c-Met Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
HGFR/c-Met Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128 kDa and the accession number is A4FUV6. | |||
TMPJ-00375 | HGF Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti... | |||
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPH-03312 | HGF Protein, Rat, Recombinant (GST) | Rat | E. coli |
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase M... | |||
TMPH-02923 | SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration... | |||
TMPH-02922 | SRPX2 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... |